http://hyperphysics.phy-astr.gsu.edu/hbase/deter.html WebJan 28, 2024 · Blinatumomab, a bispecific antibody that directs CD3 + T cells to CD19 + tumor cells, shows variable efficacy in B-progenitor acute lymphoblastic leukemia (B …
Tumor-intrinsic and -extrinsic determinants of response …
WebJan 28, 2024 · To determine tumor-intrinsic and -extrinsic determinants of response, we studied 44 adults with relapsed or refractory B-ALL (including 2 minimal residual … WebMar 13, 2024 · Intrinsic and extrinsic factors lie at the root of inter-individual and population level variability and can have marked effects on PK, PD, and the exposure-response relationship. Because of this variability, careful consideration should be given to the potential impact of intrinsic and extrinsic factors, especially when the properties of … barnburgh doncaster
Leukemia-intrinsic determinants of CAR-T response revealed by …
WebObjective: The aim of the study was to evaluate and compare specific intrinsic and extrinsic triggers of skin sensitivity between individuals with self-reported sensitive skin and non-sensitive skin. Methods: A systematic literature review was undertaken to identify intrinsic and extrinsic factors associated with sensitive skin. A 167-item ... WebJul 6, 2024 · An idiosyncratic response is uncommon, and it is sometimes impossible to understand whether it is the result of a genetic predisposition or has some other cause such as the status of the immune system. ... A major determinant of whether a toxicant will damage cells is its lipid solubility. If a toxicant is lipid-soluble, it readily penetrates ... WebOct 17, 2013 · As such, it has been hypothesised that the assembly and modification of histones at the MIEP is an intrinsic response dictated by the cellular environment. Indeed, ... Goodrum, F. Characterization of a novel Golgi apparatus-localized latency determinant encoded by human cytomegalovirus. J. Virol. 2009, 83, 5615–5629. [Google Scholar] Le, … suzuki jtz dk 150