Web30 Sep 2024 · SPOP is also required for GR50 toxicity and functions in a genetic pathway that includes cul-3, which is the canonical E3 ligase partner for SPOP. Genetic or pharmacological inhibition of SPOP in mammalian primary spinal cord motor neurons suppressed DPR toxicity without affecting DPR expression levels.
SPOP promotes ATF2 ubiquitination and degradation to …
Web4 Oct 2024 · SPOP:substrate LLPS-directed ubiquitination is an interesting new example of protein quality control of phase-separated proteins. This work provides a possible mechanism for the recruitment of ubiquitination machinery to other membraneless compartments, including stress granules, in which ubiquitin-like post-translational … Web150プラドのATFを交換してみました。ATF交換の依頼お待ちしています。お仕事のご依頼は下記へ[email protected]オンラインストアここからも ... men\\u0027s scrub warm up jacket
SPOP mutations in prostate cancer: Clinical and genomic features ...
Web12 Apr 2024 · Find many great new & used options and get the best deals for Transmax ATF DX III MV, 12X1L EA at the best online prices at eBay! Free delivery for many products! Web10 Apr 2024 · Our friends at Silencer Shop are reminding everyone that in three weeks ( April 26, 2024) they plan to stop taking new orders for tax-exempt ATF Form 1 applications. ATF’s deadline to submit all tax-exempt Form 1s is May 31, 2024 but, based on high demand, Silencer Shop expects to stop taking orders by end-of-day on April 26 to ensure all ... Web2 Mar 2024 · Conclusions: SPOP mutations define a unique subset of prostate cancers enriched for black patients, high Gleason scores, absence of ERG fusions, and Wnt pathway activation. Clinical outcomes to first-line ADT appear longer than expected for genomically-unselected patients. Somatic SPOP mutations by frequency. Mutations D130H, D130N, … men\\u0027s scrub tops